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Absolute bioavailability when receiving 100 mg of allopurinol was 67 , while taking allopurinol 300 mg – 90 .

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by inhibiting xanthine oxidase, allopurinol and its metabolite block conversion of the oxypurines hypoxanthine and xanthine to uric acid, thus decreasing serum and urine concentrations of uric acid.

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symptoms and signs including nausea, vomiting, diarrhoea and dizziness have been reported in a patient who ingested 20 g allopurinol.

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there are two unpublished reports and one published paper of women giving birth to normal offspring after receiving zyloprim allopurinol during pregnancy.

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hypersensitivity allopurinol has been associated with hypersensitivity reactions.


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